Cutaneous histoplasmosis in a patient undergoing chemotherapy: A case report

Papys Mendes 1, *, Marcos Vieira 2, Amine Essaoudi 1 and M. Oukabli 1

1 Laboratory of Anatomy and Pathological Cytology, Mohammed V Military Teaching Hospital, Rabat Faculty of
Medicine and Pharmacy, Mohammed V University, Morocco.
2 Department of Infectiology, Mohammed V Military Teaching Hospital, Rabat Faculty of Medicine and Pharmacy, Mohammed V University, Morocco.
 
Case Study
World Journal of Advanced Research and Reviews, 2024, 23(02), 1079–1081
Article DOI10.30574/wjarr.2024.23.2.2436
 
Publication history: 
Received on 03 July 2024; revised on 10 August 2024; accepted on 13 August 2024
 
Abstract: 
This is a 63 year old patient, history of diagnosed vulvar neoplasm, received 7 courses of chemotherapy. Follow-up for Hodgkin's lymphoma refractory to several lines of treatment. The history of the disease dates back 3 days before her admission with the onset of fever syndrome at 39° with a dry cough evolving in a context of preservation of the general condition, which motivates her consultation in the emergency room. She presents two swellings at the level of the foot and the hand budding keratotic, indurated well limited. These two lesions are biopsied. Histoplasmosis is retained as a diagnosis. The infection is caused by the inhalation of spores suspended in the air of Histoplasma capsulatum, a dimorphic saprophytic fungus present in soil contaminated by bird or bat droppings. Occurs as filamentous in the environment and in vitro, and yeast-like in tissues at 2-4 μm in size, usually associated with immunocompromised patients, special stains for Grocott and PAS highlight the germ.
 
Keywords: 
Vulvar; Neoplasm; Hodgkin's; Lymphoma; Histoplasmosis
 
Full text article in PDF: 
Share this