The process of blood coagulation in individuals with diabetes mellitus

Nabila Harsa Ahmad 1, *, Chrisdiana Chintya Agrilista 1, Zalfaa Firdha Yuda 1 and Indeswati Diyatri 2

1 Faculty of Dental Medicine, Airlangga University, Surabaya, Indonesia.
2 Department of Oral Biology, Faculty of Dental Medicine, Airlangga University, Surabaya, Indonesia.

 
Review Article
World Journal of Advanced Research and Reviews, 2024, 24(03), 3103-3105
Article DOI: 10.30574/wjarr.2024.24.3.3981
 
 

 

Publication history: 
Received on 18 November 2024; revised on 28 December 2024; accepted on 30 December 2024
 
Abstract: 
Background: Diabetes mellitus is a global health issue impacting around 382 million people worldwide. There is a growing number examining the impact of type 2 diabetes on alterations in the coagulation system. There are several factors that play a role in coagulation disorders. Understanding the molecular changes that occur in the coagulation process in diabetes patients can help in the development of more effective management strategies to prevent complications associated with blood coagulation.
Objectives: To assess the occurrence of blood coagulation in individuals with diabetes mellitus and identify the factors involved.
Conclusion: In individuals with diabetes, the blood coagulation process is disrupted at the molecular level due to the metabolic changes associated with the condition. Various factors contribute to coagulation disorders, including the activation of the renin-angiotensin system, inflammation, and oxidative stress.
 
Keywords: 
Diabetes Mellitus; Blood Coagulation; Literature Review; Coagulation Disorder; Type 1 Diabetes; Type 2 Diabetes
 
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